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What is Diazepam and when is it used?

Diazepam is a medicine against anxiety and states of tension. Diazepam has a calming effect in case of internal agitation, nervousness, distress and sleep disturbances associated with anxiety, as well as an anticonvulsant in epileptic seizures.

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This is a benzodiazepine which is used as a sedative and as a muscle relaxant. It is often used to treat anxiety, stress, panic attacks, and insomnia. It can also be used to control certain kinds of muscle spasms.

Diazepam is a medication that can be used to treat anxiety. It belongs to a group of medicines called benzodiazepines, which are used for short-term relief of severe or disabling anxiety. Diazepam can also help with muscle stiffness, tremors, muscle spasms, seizures, and insomnia.

 

When can't Diazepam be taken/used?

Diazepam should not be used in case of known hypersensitivity to diazepam or other medicaments, of the same group of active ingredients (benzodiazepines) or to an excipient as per composition.

It is not allowed to take Diazepam even if you suffer from muscle weakness (myasthenia gravis), severe breathing problems, awakenings at night due to interrupted breathing (sleep apnea syndrome), liver disease or in case of addiction to substances, including alcohol.

 

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When is caution required in the administration/use of Diazepam?

This medicine can reduce the ability to react, the ability to drive a vehicle and the ability to use tools or machines! It is therefore not advisable to drive a motor vehicle or operate any dangerous machine when taking Diazepam.

The danger of drug dependence

The administration of Diazepam - like that of all medicines containing benzodiazepines - can lead to drug dependence. It can occur especially in the case of uninterrupted administration for a long period of time (in some cases already after a few weeks) and, if the medication is stopped abruptly, it results in withdrawal symptoms. Agitation, anxiety, insomnia, difficulty concentrating, headaches and bouts of sweating can then arise. These phenomena usually disappear within two to three weeks.

To minimize the risk of drug dependence, please adhere to the following recommendations:

  1. Only take Diazepam when prescribed by your doctor.
  2. Never increase the dose prescribed by your doctor.
  3. Tell your doctor if you want to stop taking the medicine.
  4. The doctor will periodically decide whether therapy should be continued.
  • Administration over a long period of time (usually more than four weeks) can only take place under strict medical supervision.

Diazepam can intensify the effect of alcohol or other sedatives, such as eg. sedatives, sleeping pills, spasmolytics (against epilepsy) or painkillers.

During the treatment, it is therefore preferable to completely renounce alcoholic drinks.

Other drugs that act on the brain (e.g. sedatives, sleeping pills, antidepressants, various pain relievers, drugs for paroxysmal - antiepileptic - or muscle relaxants), as well as certain drugs for stomach ulcers, tuberculosis, mycoses, asthma or for alcohol withdrawal and Diazepam, can interact with each other in some circumstances. It is therefore permissible to take such drugs in combination with Diazepam only if the doctor agrees. You should tell your doctor if you have heart disease or if you have difficulty breathing.

Concomitant intake of Diazepam and strong pain relievers from the opioid group can induce increased sleepiness or severe breathing difficulties, leading to coma and death. It is therefore important that you recognize any signs or symptoms of severe breathing difficulties or increased sleepiness, and that if so, contact your doctor immediately.

Auxiliary substances
Tablets

If your doctor has diagnosed you with intolerance to some sugars, contact your doctor before taking this medicine.

Micro-enemas

One micro-enema contains 2.5 mg of benzoic acid and 122.5 mg of sodium benzoate per 2.5 ml corresponding to 1 mg / ml of benzoic acid and 49 mg / ml of sodium benzoate.

Benzoic acid and sodium benzoate can cause local irritation.

One micro-enema contains 1000 mg of propylene glycol per 2.5 ml corresponding to 400 mg / ml. Propylene glycol can cause skin irritation.

One micro-enema contains 37.5 mg of benzyl alcohol per 2.5 ml corresponding to 15 mg / ml.

Benzyl alcohol can cause allergic reactions and mild local irritation.

Tell your doctor or pharmacist, just in case

  • suffer from other diseases
  • suffer from allergies or
  • takes other medicines (even if purchased on his own initiative) or applies them externally!

Can Diazepam be taken / used during pregnancy or breastfeeding?

During pregnancy, it is necessary to give up Diazepam, unless the doctor considers it absolutely essential and expressly prescribes it. The use has been related to the unborn child with harmful effects.

While breastfeeding it is not recommended to take Diazepam as Diazepam and its metabolic products pass into breast milk. If treatment is unavoidable, breastfeeding should be stopped.

How to use Diazepam?

The normal adult dosage is 1 tablet or 1 micro-enema of 5 mg or 10 mg 1 to 2 times a day. The tablets should be swallowed with a glass of water or another non-alcoholic drink.

For elderly people and weak patients, the dose should not exceed 5 mg per day.

Children from 1 to 6 years : 2 mg to 5 mg per day.

Children over 6 years: 5 mg to 10 mg per day.

In any case, it is up to the doctor to determine the dosage necessary for you.

Especially if you have been taking Diazepam for more than three months and in high doses (15 mg per day and more), you should avoid stopping the treatment suddenly by gradually reducing the dosage.

Do not change the prescribed dosage on your own initiative. If you think that the action of the medicine is too weak or too strong, talk to your doctor or pharmacist.

Diazepam 5 mg and 10 mg tablets have a score line and are breakable. Diazepam 2 mg tablets have a break line and can be divided for easier taking.

What side effects can Diazepam have?

The following side effects may occur when Diazepam is taken or used:

A few days after discontinuation - especially in case of prolonged use - a temporary reappearance of the original symptoms may occur In most cases it is a natural adaptive reaction of the body that disappears quickly even without resorting to the drug. Without first consulting your doctor, it is therefore not advisable to resume taking Diazepam or a similar preparation.

Repeat treatment on prescription is possible at any time.

Drowsiness, sluggishness, lightheadedness, prolonged reaction time, muscle weakness and unsteady walking (danger of falling) may occur especially with high dosage or at the start of treatment.

In addition, the following side effects have been observed: confusion, disturbed sense of coordination, blurred consciousness, reduced attention, cardiovascular disturbances, respiratory disturbances, jaundice, constipation, depression, visual disturbances (e.g. double vision), confused pronunciation , migraine, hypotension, bladder disturbances, sexual disturbances, nausea, dry mouth or excessive ptialism, skin rash, tremor, dizziness, memory disturbances, paradoxical reactions such as eg. restlessness, restlessness, fear, nightmares, hallucinations, excitability, anger, aggression, delusional ideas, unusual behavior. In the presence of such phenomena inform the doctor.

If you notice any side effects, please contact your doctor, pharmacist, especially if they are side effects not described in this leaflet.

What else needs to be taken into account?

The medicinal product should not be used beyond the date indicated with "EXP" on the container.

Storage indication

Diazepam tablets: Store in the original package and at room temperature (15-25 ° C). Keep out of reach of children.

Diazepam rectal micro-enemas: Store in the original package, protected from light and at room temperature (15-25 ° C). Do not freeze. Keep out of reach of children.

Your doctor or pharmacist, who have detailed professional information, can give you further information.

What does Diazepam contain?

Active principles

Diazepam contains diazepam as an active ingredient. Diazepam is available in the form of 2 mg, 5 mg, 10 mg tablets and 5 mg and 10 mg micro-enemas per 2.5 ml of solution.

Diazepam Auxiliary

2 mg tablets : lactose monohydrate, pregelatinized maize starch, polysorbate 80, microcrystalline cellulose, talc, magnesium stearate.

5 mg tablets: lactose monohydrate, potato starch, polysorbate 80, microcrystalline cellulose, talc, magnesium stearate, povidone.

10 mg tablets: lactose monohydrate, potato starch, polysorbate 80, microcrystalline cellulose, talc, magnesium stearate, povidone.

Micro-enemas : benzoic acid (E210), sodium benzoate (E211), ethanol, benzyl alcohol, propylene

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