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Description

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What is Xanax and when is it used?

Xanax contains the active substance alprazolam, a substance from the benzodiazepine group. Xanax exerts an anxiolytic, relaxing and calming action. It is indicated in the treatment of states of anguish, tension and panic.

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What must also be taken into account during treatment?

The action of drugs such as Xanax, which contain benzodiazepines, can be affected if alcoholic beverages or certain other medicines are taken at the same time.

When can't  be used?

Xanax should not be used in case of hypersensitivity to benzodiazepines or one of the other constituents of the preparation and in case of pathological muscular asthenia (myasthenia gravis), severe respiratory dysfunction, interruption of breathing during sleep (sleep apnea syndrome) and severe liver dysfunction. Xanax cannot be taken together with certain drugs used to fight mycosis or with certain medicines used in the treatment of AIDS (so-called protease inhibitors).

When is caution required ?

This medicine can reduce the ability to react, the ability to drive a vehicle and the ability to use tools or machines!

Danger of addiction

As with all drugs containing benzodiazepines, taking Xanax can create a state of dependence, which occurs especially if it is taken continuously for a prolonged period (in some cases already after a few weeks) and causes symptoms of deprivation when the drug is stopped abruptly. Agitation, distress, insomnia, difficulty concentrating, headache and sweating may occur. These symptoms generally disappear after two to three weeks.

In order to reduce the risk of addiction as much as possible, follow these guidelines:

  • Only take Xanax when prescribed by your doctor.
  • Never increase the dose prescribed by your doctor.
  • Tell your doctor if you intend to stop treatment.
  • Your doctor will decide at regular intervals whether to continue the treatment.
  • Long-term use of the drug (usually beyond 4 weeks) must be done under strict medical supervision.

The concomitant use of Xanax and opioids can cause severe depression of certain brain functions with severe respiratory disorders that can lead to loss of consciousness and death and should therefore be avoided.

In patients with impaired renal or hepatic function, Xanax should be dosed with caution.

In patients suffering from depression, some mild or even severe psychic pathological symptoms (so-called manias) may occur during treatment with Xanax.

The action of Xanax is strengthened if both sedatives, strong analgesics and other drugs that act on the central nervous system, and alcoholic drinks are taken at the same time. Certain antibiotics, high blood pressure medications, depressions and some other medications can influence and strengthen the action of Xanax. Xanax can also affect the action of other drugs (e.g. lithium and digoxin). It is therefore important that you tell your doctor if you are taking any other medicines.

In elderly patients, Xanax should be administered with caution, as they react more sensitively to this medicine than younger patients.

Drug or medication abuse is a known risk with taking Xanax.

For patients who are prone to drug abuse, alcoholics and drug users, Xanax should only be administered in cases of absolute necessity and under strict medical supervision. Patients taking Xanax should also be monitored appropriately during treatment.

Patients with rare hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not take Xanax tablets.

The use of Xanax in children and adolescents below 18 years has not been investigated.

Tell your doctor or pharmacist if you have any other illnesses, suffer from allergies or take other medicines (even if bought on your own).

Can this be given during pregnancy or breastfeeding?

Xanax should not be administered during pregnancy, especially in the first three months, and during breastfeeding. If you are pregnant or planning to become pregnant, you should definitely consult your doctor.

If you take Xanax late in pregnancy or during delivery, side effects may occur in the newborn. Infants, whose mothers often took benzodiazepine-containing preparations during pregnancy, can develop addiction and thus have withdrawal reactions.

If it is necessary to take Xanax while breastfeeding, you must stop breastfeeding.

How to use ?

The doctor determines the dosage, the duration of the treatment and the time to take the tablets individually for each patient.

Usual dosage
Xanax:

The usual dosage varies from 0.5 mg to 1.5 mg per day divided into several administrations. Depending on the patient's reaction, the dose can be increased to 4 mg per day, in some cases to 6 mg per day. The tablets should be swallowed with some liquid without chewing them.

The 2mg Xanax tablet is elongated in shape and has three grooves. To divide, place the tablet on a hard surface, with the writing facing up, and press the center of the tablet with your thumb. In the same way, the two halves can be further divided. 4 parts of 0.5 mg are made from it.

Xanax retard:

Xanax retard tablets are taken one to two times a day. In case of only one daily intake it is preferable to take the tablet in the morning. The usual starting dose ranges from 0.5 mg to 1.5 mg per day. Depending on the patient's reaction, it may be necessary to increase the dose up to 4 mg per day, in some cases up to 6 mg per day. The tablets should be swallowed with some liquid and should not be chewed or divided.

Other dosage indications valid for all formulations in tablets

Elderly patients and patients whose general state of health is weakened should take a reduced dose.

Increasing or decreasing the dose should be prescribed by the doctor and the medication should be taken exactly as directed.

In particular, treatment with Xanax should never be stopped suddenly.

The use of Xanax in children and adolescents under the age of 18 has not been investigated and therefore cannot be recommended (see also 'When is caution required when administering Xanax?').

Do not change the prescribed dosage on your own initiative. If you think that the action of the medicine is too weak or too strong, talk to your doctor or pharmacist.

What are the side effects ?

Side effects occur mainly at the start of treatment and usually subside during the course of therapy or in case of dose reduction.

As with all benzodiazepines, behavioral abnormalities and paradoxical reactions such as memory disturbances, mental confusion, aggression, arousal states or hallucinations may occur in rare cases. Tell your doctor immediately if you get such symptoms.

The following side effects may occur while taking Xanax:

Very frequent (affects more than 1 user in 10): depression, drowsiness, lightheadedness, fatigue, irritability, memory impairment, dizziness, headache, speech disturbances, movement sequence disorders, dry mouth, constipation, changes in the weight.

Frequent (affects 1 to 10 users in 100) : mental confusion, disorientation, reduced sexual desire (libido), feeling anxious, insomnia, nervousness, balance disorders, coordination disorders, attention disorders, hypersomnia, lethargy, tremor, blurred vision, decreased appetite, nausea.

Occasionally (affects 1 to 10 users in 1,000) : memory lapses (amnesia), muscle weakness, drug or drug addiction.

The following side effects have also been observed since the introduction on the market:

affect disorders (hypomania, mania), hallucinations, anger, aggression, hostility, morbid restlessness, abnormal thoughts, increased psychomotor activity, drug or drug abuse, drug withdrawal syndrome, abnormal involuntary muscle contractures, stroke disorders gastrointestinal, hepatitis, liver dysfunction, jaundice, urinary incontinence, urinary retention, dermatitis, angioedema (collection of fluid in the skin and / or mucosa), increased sensitivity of the skin to light (photosensitivity), sexual dysfunction, impaired sexual sensitivity , menstrual irregularities, increased internal pressure of the eye, fluid retention p. ex. in the arms or legs (peripheral edema), hypersensitivity reactions (eg hives, swelling of the pharynx and larynx).

If you notice any side effects, please contact your doctor or pharmacist, especially if they are side effects not described in this leaflet.

What else needs to be taken into account?

The medicinal product should not be used beyond the date indicated with "EXP" on the package.

Store away from light and humidity, at room temperature (15-25 ° C) and out of reach of children.

Your doctor or pharmacist, who have detailed professional information, can give you further information.

What does it contain?

Xanax:

1 tablet of 0.25 mg contains 0.25 mg of alprazolam, is white in color, oval in shape and marked "Upjohn 29" on one side and a groove on the other side.

1 tablet of 0.5 mg contains 0.5 mg of alprazolam, is pink in color, oval in shape and marked "Upjohn 55" on one side and a groove on the other side.

1 tablet of 1 mg contains 1 mg of alprazolam, it is lilac in color, oval in shape and marked "Upjohn 90" on one side and a groove on the other side.

1 tablet of 2 mg contains 2 mg of alprazolam, is white in color, elongated in shape and is marked "U94" on one side and three grooves on both sides.

The tablets additionally contain the following auxiliary substances:

Lactose, microcrystalline cellulose, docusate sodium, anhydrous colloidal silica, corn starch, magnesium stearate, dyes: erythrosine (E127; tablets of 0.5 mg and 1 mg), indigo carmine (E132; tablets of 1 mg); preservatives: sodium benzoate (E211).

Xanax retard:

1 0.5 mg retard tablet contains 0.5 mg of alprazolam, is light blue, round in shape and marked "P&U 57" on one side.

1 tablet of 1 mg retard contains 1 mg of alprazolam, is white, round in shape and marked "P&U 59" on one side.

1 tablet of 2 mg retard contains 2 mg of alprazolam, is light blue, pentagonal in shape and is marked "P&U 66" on one side.

1 tablet of retard of 3 mg contains 3 mg of alprazolam, is white, triangular in shape and marked "P&U 68" on one side.

Retard tablets additionally contain the following auxiliary substances:

Lactose, methylhydroxypropylcellulose, colloidal silicon dioxide, magnesium stearate; dye: indigo carmine (E132; 0.5 mg and 2 mg tablets).

 

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