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Product Code: 300 mg
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Buy Gabapentin : Uses, Dosage, Side Effects, Warnings

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What is Gabapentin and when is it used?

Gabapentin is a medicine used to treat certain types of epilepsy. Gabapentin can be used on its own in patients aged 12 years and over or in combination with other medicines in patients aged 3 years and over to treat epilepsy.

Gabapentin will suppress seizures entirely or reduce the frequency of seizures.

You will be given Gabapentin in particular if your illness has not responded sufficiently to the previous therapy alone or you could not tolerate this treatment well.

Gabapentin can also be used to treat certain neuropathic pain in adults.

Prescriptened by your doctor.

Warnings before taking Gabapentin

If you are hypersensitive to gabapentin or any of the excipients contained in Gabapentin (see section “What does Gabapentin contain?”).

In what circumstances should you take caution while taking Gabapentin?

Follow all instructions given by your doctor carefully. Particular caution is required in the following cases:

Use in children: Children - especially those with pre-existing disabilities, attention deficit or behavioral disorders - may experience increased levels of aggressiveness, emotional lability and other psychological side effects. The doctor will decide whether to reduce the dose of Gabapentin or to stop treatment.
Kidneys: Tell your doctor if you have kidney disease as the dose may need to be adjusted.
Thoughts of suicide / self-harm: A small number of people being treated with anti-epileptic drugs such as Gabapentin have had thoughts of harming or killing themselves. If at any time you have these thoughts, contact your doctor immediately.
Hypersensitivity reactions:Hypersensitivity reactions, which can be serious, may occur after taking Gabapentin. They show symptoms such as difficulty breathing, swelling of the lips, throat and tongue, and a drop in blood pressure. If such symptoms occur, you must seek medical help immediately. Serious skin reactions can rarely occur. They manifest themselves through symptoms such as an itchy rash, red blistering spots on the skin, allergic swelling of the skin and mucous membrane, swelling of lymph nodes or fever. Contact your doctor or health care professional immediately if a new rash occurs or an existing rash gets worse. The doctor will decide whether treatment with Gabapentin needs to be stopped.
Muscles: In individual cases, serious muscle problems (muscle weakness, tenderness or pain) can occur. These can be caused by abnormal muscle breakdown, especially if you feel unwell or have a high temperature at the same time, which can be life-threatening and lead to kidney problems. Contact your doctor immediately if you develop unexplained muscle pain.
Drowsiness/dizziness: Gabapentin may cause sedation (drowsiness, tiredness), dizziness, confusion and similar symptoms; this can lead to accidental injuries (falls) in older people. Exercise particular caution when initiating treatment and after changing the dosage until you are familiar with the possible effects of treatment.
Abuse / Addiction: There have been cases of addiction and abuse of Gabapentin. Patients who are prone to drug abuse or excessive consumption of alcohol or drugs should talk to their health care professional before taking this medicine.
Absences: Gabapentin is generally not effective against so-called absences. It may even make this type of seizure worse in some patients. Gabapentin should therefore be used with caution in mixed forms of epilepsy that also include absenteeism.
If you have a nervous system or respiratory problems, or if you are older than 65 years, your doctor may prescribe a different dose for you.
Driving and using machines

Gabapentin may make you feel sleepy, tired, dizzy or have similar symptoms. There have also been reports of loss of consciousness, confusion, and impaired mental state. Therefore, this medicine can impair your ability to react, drive and use tools or machines! In addition, the frequency of accidents (risk of falling) can be increased. This applies even more in combination with alcohol. Therefore, you should be careful until you get used to the medicine.

Gabapentin capsules contain lactose (milk sugar). Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take Gabapentin capsules.

Interactions with other drugs

  • Opioids (strong pain relievers) can make Gabapentin more effective. If taken at the same time, possible side effects such as drowsiness can be increased. Your doctor will reduce the dose of one of the two medicines if necessary. In some cases, breathing can flatten out / slow down, which can be life-threatening. Contact your doctor immediately if you have breathing problems.
  • In particular, tell your doctor or pharmacist if you are taking or have recently taken medicines for convulsions, sleep disorders, depression, anxiety or other neurological or psychiatric problems.
  • Magnesium- or aluminum-containing antacids (medicines for stomach acidity) can reduce the absorption of Gabapentin. Gabapentin should therefore not be taken within 2 hours of taking such an antacid.
  • Interactions with other medicaments for the treatment of epilepsy and with contraceptives ("pill") have not been observed.

Tell your doctor or pharmacist if you

  • suffer from other diseases,
  • Have allergies or
  • take other medicines (including ones you have bought yourself!) or apply them externally!
  • Can Gabapentin be used during pregnancy or breastfeeding?
  • If you are pregnant or want to become pregnant, you should only use Gabapentin after consulting your doctor.

Gabapentin, the active substance in Gabapentin, is excreted in breast milk. As serious adverse effects in the infant cannot be definitively ruled out, either breast-feeding or treatment with Gabapentin should be discontinued.

Your doctor will advise you on how to do this.

Dosage of Gabapentin

Always take Gabapentin exactly as your doctor has told you. Your doctor will determine the right dose for you.

epilepsy
Adults and children from 12 years
Your doctor will usually increase the dose gradually. The starting dose is usually between 300 mg and 900 mg per day. Then the dose can be increased gradually up to a maximum of 2400 mg per day.

Gabapentin is taken three times a day.

Additional therapy for children between 3 and 12 years of age
Your doctor will decide the dose for your child based on their weight. Treatment begins with a lower starting dose which is increased slowly over 3 days. Thereafter, the usual daily dose for the treatment of epilepsy is around 30 mg / kg body weight per day. It is usually divided into 3 individual doses a day.

Weight range (kg)

Daily dose (mg / day)

17-25 /600

26-36 /900

37-50/1200

51-72/1800

Neuropathic pain in adults
Usually, the starting dose is 300 mg per day. Your doctor will then normally gradually increase the dose up to a maximum of 3600 mg per day. Gabapentin is taken three times a day.

Type of intake/duration of therapy
Gabapentin capsules and film-coated tablets should be swallowed whole with enough water. The film-coated tablets are scored and can be divided. It can be taken both during and between meals. When using it three times a day, you should make sure that no more than 12 hours pass between two times of intake. It is not necessary to make up for a missed dose of Gabapentin with an additional dose.

Do not stop taking Gabapentin until your doctor tells you to. When your epilepsy treatment is stopped, it must be done gradually over at least a week. If you stop treatment suddenly or without your doctor's advice, the risk of a seizure increases.

Treatment with Gabapentin can be carried out for an unlimited period of time under regular supervision by your doctor.

Do not change the prescribed dosage on your own. If you think that the medicine is too weak or too strong, talk to your doctor or pharmacist.

Side effects of Gabapentin

The following side effects may occur when taking Gabapentin (see also "When should you take caution when taking Gabapentin?"):

Very common (affects more than 1 in 10 people)
Drowsiness, tiredness, dizziness, movement disorders.
Common (affects 1 to 10 users in 100)
Decrease in white blood cells, bruising.
Swelling of the extremities, weight gain or weight loss.
Memory loss, confusion, depression, speech disorders, mood swings, insomnia, nervousness, eye tremors (nystagmus), thought disorders, tremors, twitching, gait disorders, decreased sensitivity to touch stimuli, vertigo, headache, increased, decreased or absent reflexes, fear, hostility, internal convulsions Restlessness, abnormal sensations such as tingling in arms and legs.
Visual disturbances such as double vision and low vision.
Vasodilatation increased blood pressure.
Cough, sore throat, runny nose, shortness of breath, pneumonia.
Constipation, changes in the teeth, inflammation of the gums, diarrhea, indigestion, increased appetite, loss of appetite, dry mouth / throat, nausea, vomiting, gas, abdominal pain.
Abrasions, acne, itchy skin, rash.
Broken bones, muscle, back and joint pain.
Impotence, urinary tract infections.
Fever, infection, cold symptoms, pain, weakness, swelling of the face, chest pain, injury from accident.
Rare (affects 1 to 10 in 10,000 users)
Difficulty breathing, shallow breathing (respiratory depression).

The following side effects have also been observed since the market launch: Hallucinations, movement disorders, ringing in the ears, heart muscle weakness, palpitations, inflammation of the pancreas, increased liver values, inflammation of the liver, jaundice, hypersensitivity reactions (can be severe, see also «When should you take care when taking Gabapentin? »), Hair loss, skin rash after strong sun exposure, inflammation of the skin / mucous membrane, muscle twitching, muscle weakness (see« When should you take caution when taking Gabapentin? »), Kidney failure, involuntary leakage of urine (urinary incontinence), fall/injuries caused by a fall, loss of consciousness, Sexual function disorders (including changes in libido, ejaculation disorders and lack of orgasm), Enlargement of the breast in men and women, high or too low blood sugar levels (mainly in diabetics).

Side effects after abrupt discontinuation of Gabapentin have also been observed. The most common were anxiety, insomnia, nausea, pain, and sweating.

If you get any side effects, talk to your doctor or pharmacist. This also applies in particular to side effects not listed in this leaflet.

What should also be noted?
The drug may only be used up to the date marked "EXP" on the container.

Storage advice
Store in the original packaging at room temperature (15-25 ° C) and out of the reach of children.

More information
Certain test strip methods for determining protein in urine (e.g. Ames N-Multistix SG®) can give false positive results when using Gabapentin.

Your doctor or pharmacist can provide you with further information. These people have the detailed information for specialists.

What does Gabapentin contain?
The 100 mg capsules are white and have a blue imprint on each capsule (“5026” / “G”).

The 300 mg capsules are yellow and have a blue print on each capsule («5027» / «G»).

The 400 mg capsules are orange and have a blue print on each capsule (“5028” / “G”).

The 600 mg film-coated tablets are white, longitudinally oval and have a break line for dividing and embossed on each side (“NT” / “16”).

The 800 mg film-coated tablets are white, longitudinally oval and have a break line for dividing and an embossing on each side (“NT” / “26”).

Active ingredients
1 capsule of 100 mg contains 100 mg gabapentin.

1 capsule of 300 mg contains 300 mg gabapentin.

1 capsule of 400 mg contains 400 mg of gabapentin.

1 film-coated tablet of 600 mg contains 600 mg gabapentin.

1 800 mg film-coated tablet contains 800 mg gabapentin.

Auxiliary materials
Capsules: lactose, corn starch and talc. The capsule shells are made of gelatine, water, titanium dioxide (E171) and sodium dodecyl sulfate. The yellow shells of the 300 mg capsules also contain yellow iron oxide (E172). The orange shells of the 400 mg capsules also contain yellow and red iron oxide (E172).

Film-coated tablets: Poloxamer 407, copolyvidone, corn starch and magnesium stearate. The film coating consists of talc, hydroxypropyl cellulose and candelilla wax.

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